What is the mechanism of action of policresulen? | Rounds What is the mechanism of action of policresulen? | Rounds
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What is the mechanism of action of policresulen?

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Policresulen Mechanism of Action

Policresulen acts as a topical chemical cauterizing agent. [1]

Tissue Effects

  • Strong acidity and protein coagulation kill bacteria and cause selective necrosis of damaged tissues. [1]
  • Denaturation of epithelial proteins occurs after contact with the drug. [1]
  • Vasoconstriction and plasma protein coagulation reduce bleeding. [1]

Antimicrobial Effects

  • Policresulen exerts antibacterial activity by strong acid–mediated effects and protein coagulation, with activity against bacteria and trichomonads described in the prescribing information. [1]

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