Plasma Renin Activity and Aldosterone Testing on ACE Inhibitors or ARBs
Plasma renin and aldosterone can be measured while a patient is taking an angiotensin-converting enzyme inhibitor (ACE inhibitor) or an angiotensin receptor blocker (ARB). [1]
ACE inhibitors and ARBs alter the aldosterone-renin ratio (ARR) interpretation by stimulating renin and suppressing aldosterone, which can reduce screening test sensitivity and create false-negative results. [2]