Auvelity (dextromethorphan/bupropion) Discontinuation Procedure
Discontinuation of AUVELITY should be managed by the prescribing clinician. [1] Stopping AUVELITY suddenly can cause serious side effects. [1]
Situations Requiring Immediate AUVELITY Discontinuation
AUVELITY should be discontinued immediately if a seizure occurs. [1] AUVELITY should be discontinued if serotonin syndrome occurs. [1] AUVELITY should be discontinued in pregnant females. [1]
Medication-Transition and Washout Considerations
If initiation of an MAOI is required, AUVELITY should be discontinued before initiating the MAOI. [1] AUVELITY should not be used within 14 days of discontinuing an MAOI. [1]
Dosing Formulation Constraints
AUVELITY tablets should be swallowed whole and should not be crushed, chewed, or divided. [1]
Patient Medication-Counseling Directives During Discontinuation
Patients should not start or stop other medicines during AUVELITY treatment without clinician guidance. [1] Patients should contact the healthcare provider for guidance if serious or concerning adverse effects occur during discontinuation. [1]
Missed-Dose Guidance During Discontinuation Episodes
If a dose is missed, the next dose should be taken at the regular time. [1] An extra dose should not be taken to make up for the missed dose. [1]