What is the formula for calculating the cerebroplacental ratio (CPR) using umbilical artery Doppler indices (such as PI or S/D ratio) and middle cerebral artery Doppler measurements in the third trimester? | Rounds What is the formula for calculating the cerebroplacental ratio (CPR) using umbilical artery Doppler indices (such as PI or S/D ratio) and middle cerebral artery Doppler measurements in the third trimester? | Rounds
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What is the formula for calculating the cerebroplacental ratio (CPR) using umbilical artery Doppler indices (such as PI or S/D ratio) and middle cerebral artery Doppler measurements in the third trimester?

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Cerebroplacental Ratio (CPR) Calculation Using Doppler Indices

The cerebroplacental ratio (CPR) is calculated as the ratio of the fetal middle cerebral artery (MCA) Doppler measurement to the fetal umbilical artery (UA) Doppler measurement.

CPR uses the same type of Doppler index for both vessels (e.g., PI with PI, or S/D with S/D).

Formula Using Pulsatility Index (PI)

CPR (PI-based)
[ \text{CPR}=\frac{\text{MCA-PI}}{\text{UA-PI}} ]

Formula Using S/D Ratio

CPR (S/D-based)
[ \text{CPR}=\frac{\text{MCA (S/D)}}{\text{UA (S/D)}} ]

Practical Index-Consistency Rules

CPR should be computed using the same Doppler index in the numerator and denominator (PI with PI, S/D with S/D).

CPR should be derived from third-trimester Doppler measurements of MCA and UA obtained in the same fetal condition/assessment session.

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