What is the ICD‑10‑CM diagnosis code for a patient with elevated low‑density lipoprotein (LDL) cholesterol and elevated total cholesterol?

Elevated LDL cholesterol and elevated total cholesterol (ICD-10-CM)

ICD-10-CM code E78.00 (Pure hypercholesterolemia, unspecified) applies to elevated LDL cholesterol with elevated total cholesterol when a more specific hypercholesterolemia subtype is not documented. [1], [2]

Code Selection

• E78.00 (Pure hypercholesterolemia, unspecified) is selected for cholesterol elevation consistent with pure hypercholesterolemia. [1], [2]

Exclusions and Related Codes

• If triglycerides are also elevated and the condition is documented as mixed hyperlipidemia, E78.2 (Mixed hyperlipidemia) is used. [3]

Documentation Requirements

• Documentation should support that the abnormality is hypercholesterolemia. [1], [2]

Coding Note

• The ICD-10-CM description for E78.00 is “Pure hypercholesterolemia, unspecified.” [1], [2]