# AI Renal / Hepatic Dose Adjustment Lookup
> Look up the FDA-label and KDIGO / Child-Pugh dose bands for any medication. Structured output + verification references. Clinical education — final dose is a clinician + pharmacy decision.

## Overview

The Renal / Hepatic Dose Adjustment Lookup returns the FDA-label and KDIGO-grounded dose bands for a single drug across renal function categories (eGFR or CrCl bands) and hepatic function categories (Child-Pugh A/B/C). Output includes label guidance, monitoring considerations, dialysis considerations where relevant, and the references the clinician should open to confirm. The tool does not recommend a final dose — final dosing remains a clinician and pharmacy decision.

## Who this is for

- Hospitalists and APPs prescribing renally / hepatically cleared agents
- Internal medicine and nephrology trainees
- Inpatient and community pharmacists

## Cited source

**FDA Drug Label + KDIGO + Sanford Guide** (2024) — FDA / KDIGO / Sanford

_Primary publication:_ Each response names the specific FDA label and KDIGO publication.

## FAQs

### Does the tool replace the FDA label?

No. It surfaces the label structure for fast review; the clinician should always confirm against the current FDA label before prescribing.

### Are dialysis-specific doses included?

Yes when the FDA label or KDIGO provides them. Intermittent vs continuous dialysis often differ; verify with your renal pharmacist.

### Is Child-Pugh always applicable?

No. Many drugs have only renal-elimination data and no hepatic-impairment guidance. The tool will note when hepatic data is unavailable.

### Can I look up multiple drugs at once?

One drug per request to keep output focused. For polypharmacy, run several lookups or escalate to clinical pharmacy.

### What if the FDA label is silent?

The tool will surface that gap, point to alternative references (Sanford, KDIGO, Aronoff), and recommend pharmacy review.

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_Rounds AI is a citation-first clinical AI assistant. It supports clinical reasoning by surfacing cited information and is not a substitute for independent clinical judgement._