# AI Empiric Antibiotic Therapy Lookup
> Look up the empiric antibiotic regimens that guidelines commonly list for a given infection site + setting. Grounded in IDSA / SIS / WHO guidelines. Clinical education — verify against local antibiogram.

## Overview

The Empiric Antibiotic Therapy Lookup surfaces guideline-grounded empiric regimens by infection site and clinical setting. For each request, the tool returns the named guideline (typically IDSA, SIS, WHO, or specialty equivalent), first-line regimens, alternatives for documented allergies, common pathogen coverage, what the clinician must verify before prescribing (local antibiogram, renal/hepatic dosing, drug interactions, pregnancy/lactation), and red flags that warrant immediate specialist input. The tool does not prescribe and does not substitute for institutional antimicrobial stewardship review.

## Who this is for

- Hospitalists and emergency physicians starting empiric therapy
- Internal medicine residents on inpatient services
- Pharmacists and antimicrobial stewardship teams

## Cited source

**IDSA / SIS / specialty guidelines** (2024) — IDSA / SIS

_Primary publication:_ Each response names the specific guideline (e.g. IDSA/ATS 2019 CAP, IDSA 2010 cIAI, etc.).

## FAQs

### Does the tool know my hospital's antibiogram?

No. Local antibiogram and resistance patterns must be applied by the clinician or pharmacist before finalising therapy. The tool always emits a 'must_check_before_acting' field reminding the user.

### Will it adjust for renal function?

Not directly. Use the Renal / Hepatic Dose Adjustment Lookup tool, the FDA label, or institutional pharmacy after the empiric regimen is chosen.

### Can I trust the duration recommendations?

Durations follow the cited guideline at time of training. Recent guideline updates (e.g. shortened CAP courses) should be verified against the current IDSA / ATS publication.

### Does it cover paediatrics?

Paediatric regimens follow paediatric IDSA / AAP guidance; identify the patient population in the input. Always verify paediatric weights and renal status.

### What about culture-directed therapy?

Once cultures and susceptibilities return, narrow therapy per stewardship principles; the empiric regimens are starting points, not endpoints.

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_Rounds AI is a citation-first clinical AI assistant. It supports clinical reasoning by surfacing cited information and is not a substitute for independent clinical judgement._