Lidocaine Use During Ceftriaxone IV Infusion
Lidocaine is not indicated for reconstitution or dilution of ceftriaxone (Rocephin) for IV infusion. [1]
Rocephin Reconstitution for IV Infusion
For an IV infusion, a 1 g vial of ceftriaxone should be reconstituted with an appropriate IV diluent at a labeled diluent volume of 9.6 mL, yielding ~100 mg/mL ceftriaxone after reconstitution. [1]
Lidocaine Contraindication for IV Diluent Selection
The prescribing directions specify reconstitution for IV use with an appropriate IV diluent and do not provide a lidocaine dose for IV reconstitution. [1]
Practical Answer to the Dose Question
Lidocaine should not be added to a 1 g vial of Rocephin when preparing an IV infusion preparation. [1]
IV Infusion Concentration Target
The infused ceftriaxone solution should be prepared to a concentration of 10 mg/mL to 40 mg/mL (lower concentrations may be used). [1]