Loratadine Dosing Frequency in Older Patients With Renal or Hepatic Impairment
Loratadine is dosed 10 mg orally once daily in adults and children aged 6 years and older, with a maximum of 1 tablet (10 mg) within 24 hours. [1] No dosage adjustment is recommended for older patients. [2]
Standard Dosing Frequency
- Loratadine 10 mg once daily is recommended for adults and children aged 6 years and older. [1]
Impaired Renal Function
- No dosage adjustments are required in patients with renal insufficiency. [2]
Hepatic Impairment
- In severe hepatic impairment, a lower initial dose is recommended due to reduced clearance of loratadine. [2]
- Severe hepatic impairment dosing frequency: loratadine 10 mg every other day is recommended for adults and children weighing more than 30 kg. [2]
Dosing Frequency Summary for Older Patients
- Older patients with renal insufficiency: 10 mg once daily. [1], [2]
- Older patients with severe hepatic impairment: 10 mg every other day (for patients weighing more than 30 kg). [2]