Intragastric pH Response to Oral Magnesium Oxide in Dyspepsia
Published intragastric-pH monitoring studies in dyspepsia that specifically quantify how long oral magnesium oxide takes to raise intragastric pH were not identified in the available literature.
Expected Time Course for Alkalinizing Antacids
Clinical intragastric pH studies of rapid-acting antacid formulations containing magnesium (as magnesium hydroxide in Al/Mg hydroxide antacids) show that gastric pH increases essentially immediately after dosing. Effects of a new effervescent cimetidine formulation on gastric acidity in healthy subjects
Practical Interpretation
The onset of intragastric pH elevation reported for magnesium-containing antacids is minutes (essentially immediate). Effects of a new effervescent cimetidine formulation on gastric acidity in healthy subjects
Evidence Gap
A dyspepsia-specific, magnesium-oxide-specific intragastric pH time-to-rise value (e.g., time to reach pH >3 or pH >4) was not located in the accessible sources.