In chronic aspirin users, what effect estimates did Semeya et al. (2026) report for Helicobacter pylori eradication on the risk of peptic ulcer bleeding and on cardiovascular disease progression? | Rounds In chronic aspirin users, what effect estimates did Semeya et al. (2026) report for Helicobacter pylori eradication on the risk of peptic ulcer bleeding and on cardiovascular disease progression? | Rounds
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In chronic aspirin users, what effect estimates did Semeya et al. (2026) report for Helicobacter pylori eradication on the risk of peptic ulcer bleeding and on cardiovascular disease progression?

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Semeya et al. (2026) reported that persistent Helicobacter pylori infection after eradication was associated with higher risk of peptic ulcer bleeding (PUB) than successful eradication in chronic aspirin users, with PUB prevalence of 8.7% at 6 weeks and 11.9% at 6 months with persistent infection versus 1.5% at 6 weeks and 3.7% at 6 months with successful eradication (P < 0.001). Semeya et al., 2026 (title page/record)

For cardiovascular disease progression, Semeya et al. (2026) reported a hazard ratio (HR) of 3.5 (P < 0.001) associated with H. pylori positivity/persistence during follow-up. Semeya et al., 2026 (title page/record)

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