Menstrual cycle timing after miscarriage during letrozole therapy
Luteal phase function from the conception cycle does not continue after pregnancy tissue is passed. A new cycle is typically counted from the first day of the next menstrual bleeding after early pregnancy loss. [1], [2]
Expected return of menses after early pregnancy loss
Menstrual periods usually return within about 4 to 6 weeks after an abortion. [1]
Ovulation timing after miscarriage
Ovulation may resume as early as about 10 days after abortion. [2]
Practical restart timing for letrozole cycles
Letrozole for ovulation induction is generally continued until the pregnancy test timing or discontinued if not pregnant, followed by starting the next treatment cycle in sequence when the next menstrual cycle begins. [4]
Cycle-length implications for progesterone and luteal-phase assumptions
Because ovulation may recur soon after pregnancy loss, luteal-phase duration from the prior pregnancy cycle is not used to determine the timing of the next letrozole cycle. [2], [3]