Do corticosteroids cause abdominal distension? | Rounds Do corticosteroids cause abdominal distension? | Rounds
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Do corticosteroids cause abdominal distension?

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Corticosteroid-Associated Abdominal Distension

Corticosteroids can cause abdominal distension as an adverse gastrointestinal effect. [1,2]

Evidence From Drug Labeling

Prednisone labeling reports abdominal distention among adverse reactions reported with prednisone or other corticosteroids. [1]

Mechanism and Clinical Context

Corticosteroid therapy is associated with multiple gastrointestinal adverse effects. [2]

Clinical Relevance

New or worsening abdominal distension during corticosteroid use should prompt evaluation for other causes of abdominal distension, including constipation, medication-related gastrointestinal irritation, and complications related to the underlying condition. [1,2]

When Immediate Evaluation Is Needed

Urgent evaluation is needed for abdominal distension accompanied by severe abdominal pain, vomiting, gastrointestinal bleeding, fever, or signs of obstruction. [1,2]

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