After taking Motrin (ibuprofen) 600 mg, how much Aleve (naproxen) may I take for the remainder of the day? | Rounds After taking Motrin (ibuprofen) 600 mg, how much Aleve (naproxen) may I take for the remainder of the day? | Rounds
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After taking Motrin (ibuprofen) 600 mg, how much Aleve (naproxen) may I take for the remainder of the day?

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NSAID switching (ibuprofen 600 mg to naproxen/Aleve within the same day)

Aleve (naproxen) should not be taken the same day as ibuprofen, because taking two NSAIDs together increases risk without added benefit. [1] [2]

Immediate answer for the remainder of the day

Additional Aleve doses for the remainder of the day are not recommended after taking ibuprofen 600 mg. [1] [2]

Safer pain control alternatives

Acetaminophen is an alternative for pain or fever when avoiding additional NSAIDs is preferred. [3]

Why dual NSAID use is discouraged

Concomitant use of naproxen with other NSAIDs increases risk of GI toxicity, with little or no increase in efficacy. [4]

When to seek urgent help

Emergency evaluation is recommended for symptoms of GI bleeding (vomiting blood or black/tarry stools) or for signs of an allergic reaction (swelling of face/lips, trouble breathing). [2]

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